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But the solvents, flavorings and additives in the liquid base, after vaporization, expose users to multiple insults to the respiratory tract and blood vessels. Impact observed in volunteers who used an e-cigarette just once Wehrli noted that they observed these striking changes after the participants (all of whom never smoked previously) used an e-cigarette a single time

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This observational study couldn't prove that vaping caused the cigarette smoking, but while firm evidence on how e-cigarettes are changing behaviors is lacking, some researchers are concerned